Guide to  

                          the Genetics of

                  Polycythaemia Vera (Rubra)


                  Essential Thrombocythaemia

                              'PV & ET'


Prof. Louis Henri Vaquez

The condition later to be called Polycythaemia Vera was first described in Paris by Louis Henri Vaquez, who in 1892 wrote a paper entitled: 'Sur une forme spéciale de cyanose s'accompagnant d'hyperglobulie excessive et persistante'          Born: 27 August 1860 - Paris 03e, 75, Paris, Ile-de-France, FRANCE Died: 15 April 1936 - Paris 17e, 75, Paris, Ile-de-France, FRANCE Buried: Crouy-en-Thelle, 60, Oise, Picardie, FRANCE Obituary: British Medical Journal 1936 Apr 25. Professor Louis HENRI VAQUEZ, who died at his home in Paris on April 15th, was born in Paris on August 27th, 1860. As well as being professor at the Faculty of Medicine of Paris he was a hospital physician, a member of the Academy of Medicine, and an officer of the Legion of Honour. Even before radiology had become a science he had made his mark as a specialist in diseases of the heart, and it was largely in connexion with such diseases that he enjoyed an international reputation as a consultant. To many medical men outside his own country he was best known as the inventor of the sphygmometer which bears his name. See also: https://en.wikipedia.org/wiki/Louis_Henri_Vaquez http://www.whonamedit.com/doctor.cfm/1689.html https://gw.geneanet.org/joelchirol?lang=fr&n=vaquez&oc=0&p=louis+henri https://wellcomecollection.org/works/gmefmn38 And these lovely paintings by Edouard Vuillard show Dr Vasquez at work and Madame Vaquez at home (c) Musée d'Orsay, Paris
         Sir William Osler (1849–1919) Also described patients with Polycythemia Vera.              Born: 12 July 1849 Bond Head, Canada Died: 29 December 1919 Oxford, UK See also: https://en.wikipedia.org/wiki/William_Osler https://circulatingnow.nlm.nih.gov/2017/08/30/our-dear-laddie-has-been-taken-edward-revere-osler-killed-in-flanders-30-august-1917/

Epstein, E., and Goedel, A.

Two Austrian doctors Epstein & Goedel first described the condition later called Essential Thrombocythaemia in 1934 in their paper: Hämorrhagische Thrombocythämie bei vasculärer Schrumpfmilz. Virchows Archiv für pathologische Anatomie und Physiologie und für klinische Medizin March 1934, Volume 292, Issue 2, pp 233–248 Click to see the first 2 pages - in German Also see: https://link.springer.com/article/10.1007%2FBF01891529